So I have assumed myself to have NCGI after negative serology a couple of years back. I am doubting this now, thinking back, so I figured maybe I'd have the genetic test done, and if low risk, not bother with the gluten challenge and testing, and just stop worrying.
Wrong!
Here's my results, hoping someone out there can tell me what my risk is (like 2%, 5% etc) since I can NOT for the life of me find this info.
Just fyi, I do have ankylosing spondylitis (diagnosed 2 1/2 years ago, went off gluten then after negative serology). I also have HLA-B27, feeling like I somewhat got the short end of the genetic lottery stick!!
Results: Positive for celiac disease-associated HLA alleles. (done by Kimball genetics)
Results: DQ2 (DQ!a*05/DQB1*02): positive
DQA1*05:01 or *05:05 detected
DQB1*02:01 or *02:02 Detected
DQ8 (DQB1*03:02): Positive
DQB1*03:02 Detected
I know 20-30% of the population have DQ2, but I wonder how many have DQ8? And how many people have both, like me?
If anyone has wise words, I'd love to hear them. In the meantime, I'm 2 months on lots of gluten, feeling tired, irritable, poor concentration, itchy all over, some mouth sores, joint pains, lots of the big C, gassy, upper abdo pains after eating and kind of heart burn feeling, and little (not itchy) bumps all over my neck, back and shoulders. I am having my labs done this week, then booking an endo regardless of the results. Then, going back off gluten, no matter what!! I don't do strict gluten avoidance though (as previously thought NCGI), and don't want to if I don't have to. I felt fine with that ....
Wishing I had my results already - waiting is no fun!!
Thanks
Wrong!
Here's my results, hoping someone out there can tell me what my risk is (like 2%, 5% etc) since I can NOT for the life of me find this info.
Just fyi, I do have ankylosing spondylitis (diagnosed 2 1/2 years ago, went off gluten then after negative serology). I also have HLA-B27, feeling like I somewhat got the short end of the genetic lottery stick!!
Results: Positive for celiac disease-associated HLA alleles. (done by Kimball genetics)
Results: DQ2 (DQ!a*05/DQB1*02): positive
DQA1*05:01 or *05:05 detected
DQB1*02:01 or *02:02 Detected
DQ8 (DQB1*03:02): Positive
DQB1*03:02 Detected
I know 20-30% of the population have DQ2, but I wonder how many have DQ8? And how many people have both, like me?
If anyone has wise words, I'd love to hear them. In the meantime, I'm 2 months on lots of gluten, feeling tired, irritable, poor concentration, itchy all over, some mouth sores, joint pains, lots of the big C, gassy, upper abdo pains after eating and kind of heart burn feeling, and little (not itchy) bumps all over my neck, back and shoulders. I am having my labs done this week, then booking an endo regardless of the results. Then, going back off gluten, no matter what!! I don't do strict gluten avoidance though (as previously thought NCGI), and don't want to if I don't have to. I felt fine with that ....
Wishing I had my results already - waiting is no fun!!
Thanks









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